Molecular Diagnostics Solutions
Tailored Enzymes for Diverse Applications
Molecular diagnostics offer highly sensitive, accurate, and rapid genetic-level testing for a wide range of scenarios. Varied sample types, targets, technologies, and applications drive the need for specialized molecular diagnostics reagents and kits.
Premium Selection of High-Quality Enzymes
GCATbio leverages enzyme engineering, enzymological characterization, buffer optimization, process development, and application testing to deliver a premium portfolio of advanced and specialty molecular biology enzymes, expertly screened and tailored to address different needs. Available in various formats and packaging, our products can also be customized to your specifications.
Our ultra-high-throughput microdroplet screening platform enables screening of 10⁷droplets per day, turbocharging variant screening for molecular biology enzymes.
By integrating novel enzyme mining and chimeric scaffold design with variant library construction methods (e.g., error-prone PCR, rational/semi-rational design, and site saturation mutagenesis) and selection strategies (e.g., compartmentalized self-replication), we have developed high-fidelity PCR polymerases with exceptional amplification efficiency and sensitivity.
Error-prone PCR combined with compartmentalized self-replication facilitates engineering of Taq polymerases tailored for diverse applications, such as multiplex PCR and direct blood multiplex PCR.
Utilizing structural simulations and computational modeling, we generate precise, high-quality variant libraries to derive reverse transcriptases with markedly improved inhibitor tolerance, reverse transcription efficiency, template switching rate, and processivity, while minimizing residual host genomic DNA and contaminating nucleases through optimized fermentation and purification processes.
We have scaled up processes for MGI sequencing enzymes, achieving consistent supply.
Featured Products
TransFlex III Reverse Transcriptase : suitable for Complex Real-World Samples
Engineered from wild-type M-MLV by mutagenesis and directed screening, TransFlex III Reverse Transcriptase exhibits elevated thermostability, template affinity,processivity, and inhibitor resistance, enabling a broader range of downstream applications.
Jupiter HS Taq DNA Polymerase
This antibody-mediated hot-start Taq DNA polymerase can be paired with different buffers for use in diverse applications, including genotyping, SNP typing, and HTS library preparation.
Mars HiFi PCR ReadyMix (2X): Exceptional Value for Money
Optimized for high-fidelity PCR, this cost-effective solution is a ready-to-use 2× master mix containing all components except primers and template. Simply add these to run your PCR reaction.reaction.
Molecular Diagnostics Solutions
Committed to providing IVD customers with high-quality molecular biology enzymes and reagents, GCATbio has developed a rich portfolio of basic, universal PCR products to meet diverse needs for sensitivity, specificity, inhibition tolerance, turnaround times, and ease of use.
Oligo Synthesis and Enzyme OEM
Oligo Synthesis
GCATbio has developed a proprietary solid-phase high-throughput synthesizer that utilizes barcoded carriers and signal recognition systems for microchip-based massive in parallel synthesis (mMPS) of oligonucleotides. Equipped with China's first automated modular DNA synthesis and assembly platform, we supply your qPCR experiments with reliable primers and probes, featuring tightly specified molecular weight, purity, and fluorescent modifications, excellent lot-to-lot consistency, and minimal exogenous contamination that eliminates false positives.
Custom Enzymes
Different applications require different enzymes for their specialized functions under specific conditions. Following careful dissection of performance criteria based on customer needs, we screen enzyme libraries and characterize candidates to offer custom enzyme development, product optimization, and custom manufacturing and packaging services tailored to your unique requirements.
· High-density fermentation in 5 L–500 L bioreactors for milligram- to kilogram-scale enzyme scale-up and production.
· Proven supply capabilities, including consistent 2,000 L annual sequencing enzyme production over 3 years.
· ISO 9001 and ISO 13485 certified; GMP-compliant quality management system.
Interested? Visit our website or contact our team.